STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (862 aa)    
Predicted Functional Partners:
MAP3K9
Mitogen-activated protein kinase kinase kinase.
   
  0.921
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
 0.919
MAP3K10
Mitogen-activated protein kinase kinase kinase 10.
   
  0.890
HTT
Huntingtin.
   
 0.746
CDC42
Uncharacterized protein.
   
 0.697
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
  0.607
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.599
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
    
 
 0.591
VPS13A
Vacuolar protein sorting 13 homolog A.
      
 0.583
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
    
  0.553
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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