Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)    
Predicted Functional Partners:
PRPF6
Pre-mRNA processing factor 6.
   
 0.995
PRPF3
Pre-mRNA processing factor 3.
   
 0.987
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
   
 0.986
DDX23
DEAD-box helicase 23.
   
 0.984
PRPF31
Pre-mRNA processing factor 31.
   
 0.983
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
   
 0.981
PRPF4
Pre-mRNA processing factor 4.
   
 0.981
PRPF8
Pre-mRNA processing factor 8.
   
 0.980
SNRPD2
Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.
    
 0.962
UBL5
Ubiquitin like 5.
    
 0.960
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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