GIGYF2 protein (Loxodonta africana) - STRING interaction network

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GIGYF2

GRB10 interacting GYF protein 2. (1283 aa)

Predicted Functional Partners:

EIF4E2

0.967

ZNF598

0.909

GRB10

0.851

TNRC6C

0.833

DIS3L

0.813

DDX6

0.755

KCTD4

0.656

EDF1

0.640

CNOT7

0.602

AGO2

0.599

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	CNOT7	ENSLAFP00000010792	ENSLAFP00000000195	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	CCR4-NOT transcription complex subunit 7.	0.808
AGO2	DDX6	ENSLAFP00000010792	ENSLAFP00000009220	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.967
AGO2	GIGYF2	ENSLAFP00000010792	ENSLAFP00000001519	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	GRB10 interacting GYF protein 2.	0.599
AGO2	TNRC6C	ENSLAFP00000010792	ENSLAFP00000009312	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Trinucleotide repeat containing adaptor 6C.	0.992
CNOT7	AGO2	ENSLAFP00000000195	ENSLAFP00000010792	CCR4-NOT transcription complex subunit 7.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.808
CNOT7	DDX6	ENSLAFP00000000195	ENSLAFP00000009220	CCR4-NOT transcription complex subunit 7.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.850
CNOT7	GIGYF2	ENSLAFP00000000195	ENSLAFP00000001519	CCR4-NOT transcription complex subunit 7.	GRB10 interacting GYF protein 2.	0.602
CNOT7	TNRC6C	ENSLAFP00000000195	ENSLAFP00000009312	CCR4-NOT transcription complex subunit 7.	Trinucleotide repeat containing adaptor 6C.	0.770
DDX6	AGO2	ENSLAFP00000009220	ENSLAFP00000010792	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.967
DDX6	CNOT7	ENSLAFP00000009220	ENSLAFP00000000195	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	CCR4-NOT transcription complex subunit 7.	0.850
DDX6	DIS3L	ENSLAFP00000009220	ENSLAFP00000005772	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.408
DDX6	GIGYF2	ENSLAFP00000009220	ENSLAFP00000001519	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	GRB10 interacting GYF protein 2.	0.755
DDX6	TNRC6C	ENSLAFP00000009220	ENSLAFP00000009312	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Trinucleotide repeat containing adaptor 6C.	0.562
DIS3L	DDX6	ENSLAFP00000005772	ENSLAFP00000009220	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.408
DIS3L	EIF4E2	ENSLAFP00000005772	ENSLAFP00000009651	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	0.930
DIS3L	GIGYF2	ENSLAFP00000005772	ENSLAFP00000001519	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	GRB10 interacting GYF protein 2.	0.813
DIS3L	ZNF598	ENSLAFP00000005772	ENSLAFP00000023973	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Zinc finger protein 598.	0.677
EDF1	GIGYF2	ENSLAFP00000029322	ENSLAFP00000001519	Endothelial differentiation related factor 1.	GRB10 interacting GYF protein 2.	0.640
EDF1	ZNF598	ENSLAFP00000029322	ENSLAFP00000023973	Endothelial differentiation related factor 1.	Zinc finger protein 598.	0.519
EIF4E2	DIS3L	ENSLAFP00000009651	ENSLAFP00000005772	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.930

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