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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
   
 0.999
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.999
XPA
XPA, DNA damage recognition and repair factor.
    
 0.990
SLX4
SLX4 structure-specific endonuclease subunit.
   
 0.976
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.930
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
   
 
 0.926
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
     
 0.923
FANCG
FA complementation group G.
    
 0.916
FANCD2
FA complementation group D2.
     
 0.915
FANCB
FA complementation group B.
    
 0.897
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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