Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)    
Predicted Functional Partners:
METTL3
Methyltransferase like 3; Belongs to the MT-A70-like family.
  
 
0.998
WTAP
WT1 associated protein.
   
 0.997
VIRMA
Vir like m6A methyltransferase associated.
    
 0.935
METTL4
Methyltransferase like 4; Belongs to the MT-A70-like family.
     
 0.915
YTHDF1
YTH N6-methyladenosine RNA binding protein 1.
  
 
 
 0.883
ALKBH5
AlkB homolog 5, RNA demethylase.
   
  
 0.858
RBM15
RNA binding motif protein 15.
    
 0.845
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
   
  
 0.835
YTHDC2
YTH domain containing 2.
    
 
 0.813
FTO
FTO alpha-ketoglutarate dependent dioxygenase.
   
  
 0.808
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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