STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRYBA4Crystallin beta A4; Belongs to the beta/gamma-crystallin family. (196 aa)    
Predicted Functional Partners:
CRYBB1
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
   
 
 0.915
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.753
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.697
GRIFIN
Galectin.
   
  
 0.688
CRYBB3
Crystallin beta B3; Belongs to the beta/gamma-crystallin family.
   
 
 0.660
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
      
 0.655
CRYAB
Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
 
 0.629
GNB1
G protein subunit beta 1.
      
 0.613
CRYGS
Crystallin gamma S; Belongs to the beta/gamma-crystallin family.
   
  
 0.602
GRK1
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      
 0.600
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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