Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)    
Predicted Functional Partners:
PTPN13
Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
    
 0.933
SNTA1
Syntrophin alpha 1.
    
   0.775
SNTB2
PH domain-containing protein.
    
   0.687
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.673
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
   0.649
TM2D2
TM2 domain containing 2.
      
 0.636
PLEKHA8
Pleckstrin homology domain containing A8.
      
 0.596
ZMAT4
Zinc finger matrin-type 4.
      
 0.577
TACC1
Transforming acidic coiled-coil containing protein 1.
    
 0.566
KLHL21
Kelch like family member 21.
      
 0.565
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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