STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFKBIZNFKB inhibitor zeta. (719 aa)    
Predicted Functional Partners:
NFKB1
Nuclear factor kappa B subunit 1.
   
0.950
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.935
IL36RN
Interleukin-1.
      
 0.625
TRAF3IP2
TRAF3 interacting protein 2.
    
 0.618
AKIRIN2
Akirin 2.
    
 
 0.603
DUSP5
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
 0.593
TNFAIP3
TNF alpha induced protein 3.
   
 
 0.546
IL36G
Interleukin-1.
      
 0.524
REL
REL proto-oncogene, NF-kB subunit.
   
 0.523
RELB
RELB proto-oncogene, NF-kB subunit.
   
 0.496
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.