Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CNNM3Cyclin and CBS domain divalent metal cation transport mediator 3. (432 aa)    
Predicted Functional Partners:
GMPS
Guanine monophosphate synthase.
    
 0.587
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.547
PTP4A1
Protein tyrosine phosphatase 4A1.
    
 
 0.469
PTP4A2
Protein tyrosine phosphatase 4A2.
    
 
 0.469
TMEM241
Transmembrane protein 241.
   
  
 0.448
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
 0.411
G3UL45_LOXAF
Uncharacterized protein; Belongs to the 5'-nucleotidase family.
    
 0.411
PTP4A3
Protein tyrosine phosphatase 4A3.
    
 
 0.407
ITPRIP
Inositol 1,4,5-trisphosphate receptor interacting protein.
     
 0.404
MCM8
MCM domain-containing protein; Belongs to the MCM family.
   
  
 0.401
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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