STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUZD1Uncharacterized protein. (608 aa)    
Predicted Functional Partners:
ALCAM
Activated leukocyte cell adhesion molecule.
    
 0.610
ZPLD1
Zona pellucida like domain containing 1.
      
 0.575
FPR1
Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
  
 0.495
HBA
Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues.
    
 0.488
G3TGU5_LOXAF
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.481
SFTPD
Surfactant protein D.
   
 0.459
LOC100658044
Globin E1; Belongs to the globin family.
    
 0.458
LOC100657757
GLOBIN domain-containing protein; Belongs to the globin family.
    
 0.458
HBB/D
Hemoglobin subunit delta; Belongs to the globin family.
    
  0.440
G3UD77_LOXAF
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
  
 0.439
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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