STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYRP1Tyrosinase related protein 1. (537 aa)    
Predicted Functional Partners:
DCT
Dopachrome tautomerase.
  
 
0.936
OCA2
OCA2 melanosomal transmembrane protein.
   
  
 0.835
MITF
Melanocyte inducing transcription factor.
    
 0.736
SLC45A2
Solute carrier family 45 member 2.
   
 
 0.714
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.679
MLANA
Uncharacterized protein.
   
  
 0.677
GPR143
G protein-coupled receptor 143.
   
 
 0.593
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.576
ASIP
Agouti signaling protein.
      
 0.551
SLC45A1
Solute carrier family 45 member 1.
   
 
 0.531
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.