STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MSX2Msh homeobox 2. (267 aa)    
Predicted Functional Partners:
MSX1
Msh homeobox 1.
  
0.948
IRF3
IRF tryptophan pentad repeat domain-containing protein.
   
  
 0.660
RUNX2
RUNX family transcription factor 2.
    
 0.618
AVPR1A
Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
    
 
 0.589
SPEN
Spen family transcriptional repressor.
    
 
 0.540
DLX5
Distal-less homeobox 5.
   
0.531
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.526
SPDEF
SAM pointed domain containing ETS transcription factor.
      
 0.525
DLX3
Distal-less homeobox 3.
   
 0.524
BGLAP
Osteocalcin; Binds strongly to apatite and calcium.
      
 0.519
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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