STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (623 aa)    
Predicted Functional Partners:
DCAF1
DDB1 and CUL4 associated factor 1.
    
 
 0.931
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 
 0.859
TK2
Thymidine kinase 2.
    
 
 0.852
CCNA2
Cyclin A2; Belongs to the cyclin family.
    
 
 0.839
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 
 0.820
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
      
 0.780
MEIOB
Meiosis specific with OB-fold.
   
  
 0.774
DDB1
Damage specific DNA binding protein 1.
    
 
 0.768
HMBOX1
Homeobox containing 1.
      
 0.743
NAT10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
      
 0.737
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.