STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTN5Netrin 5. (485 aa)    
Predicted Functional Partners:
DCC
DCC netrin 1 receptor.
    
 0.746
NEO1
Neogenin 1.
    
 0.746
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
    
 0.742
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
    
 0.602
G3UI35_LOXAF
Uncharacterized protein.
    
 0.602
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.600
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
    
 
 0.585
COL3A1
Collagen type III alpha 1 chain.
      
 0.584
TMEM19
Transmembrane protein 19.
      
 0.579
DSCAM
DS cell adhesion molecule.
   
 0.578
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.