STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM14Tripartite motif containing 14. (440 aa)    
Predicted Functional Partners:
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.809
MAVS
Mitochondrial antiviral signaling protein.
    
 0.631
TRAT1
T cell receptor associated transmembrane adaptor 1.
   
  
 0.570
ACSM3
Acyl-CoA synthetase medium chain family member 3.
      
 0.559
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.535
PPP6C
Serine/threonine-protein phosphatase.
   
 
 0.531
MSS51
MSS51 mitochondrial translational activator.
   
  
 0.515
SPINK7
Serine peptidase inhibitor, Kazal type 7 (putative).
      
 0.509
RNASE1
Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family.
    
 
 0.485
TRIM38
Tripartite motif containing 38.
   
0.483
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.