STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)    
Predicted Functional Partners:
SDK1
Sidekick cell adhesion molecule 1.
   
  
 0.558
NCOR1
Nuclear receptor corepressor 1.
    
 
 0.552
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.549
TMOD1
Tropomodulin 1.
   
 
 0.547
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.542
DHFR
DHFR domain-containing protein.
    
 0.533
RPL7L1
Ribosomal protein L7 like 1.
   
  
 0.510
GSN
Gelsolin.
   
 
 0.495
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.485
DBN1
Drebrin 1.
   
 
 0.476
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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