STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF10Rho guanine nucleotide exchange factor 10. (1356 aa)    
Predicted Functional Partners:
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
    
 0.695
ARHGEF33
DH domain-containing protein.
     
 0.649
SPSB2
SplA/ryanodine receptor domain and SOCS box containing 2.
    
   0.586
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
      
 0.578
TRIM67
Tripartite motif containing 67.
    
 
 0.568
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.564
NDRG1
N-myc downstream regulated 1.
      
 0.561
STING1
Transmembrane protein 173.
   
 0.548
RHOH
Ras homolog family member H.
   
 0.525
CDC42
Uncharacterized protein.
   
 0.511
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.