STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFRCTransferrin receptor. (770 aa)    
Predicted Functional Partners:
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
    
 0.995
G3T9G3_LOXAF
Uncharacterized protein.
  
 0.983
GAK
Cyclin G associated kinase.
    
 0.948
HJV
Hemojuvelin BMP co-receptor.
     
 0.846
LTF
Lactotransferrin; Belongs to the transferrin family.
  
 0.840
EPOR
Erythropoietin receptor.
    
 0.759
MELTF
Melanotransferrin; Belongs to the transferrin family.
  
 0.730
EEA1
Early endosome antigen 1.
      
 0.723
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
    
 0.723
LOC100658724
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
    
 0.679
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.