Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIBP2PPFIA binding protein 2. (869 aa)    
Predicted Functional Partners:
PPFIBP1
PPFIA binding protein 1.
    
  0.838
TBC1D1
TBC1 domain family member 1.
    
 
 0.792
TBC1D4
TBC1 domain family member 4.
    
 
 0.792
CRK
CRK proto-oncogene, adaptor protein.
    
   0.765
RARRES2
Retinoic acid receptor responder 2.
      
 0.618
ASNS
Asparagine synthetase [glutamine-hydrolyzing].
      
 0.578
GLOD5
Glyoxalase domain containing 5.
      
 0.576
PTPRD
Protein tyrosine phosphatase receptor type D.
     
 0.569
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
      
 0.559
CX3CL1
C-X3-C motif chemokine ligand 1.
      
 0.554
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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