Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP4Poly [ADP-ribose] polymerase. (1241 aa)    
Predicted Functional Partners:
G3UBL3_LOXAF
Uncharacterized protein.
   
 
 0.966
PARP3
Poly [ADP-ribose] polymerase.
     
 0.949
G3TVZ6_LOXAF
Uncharacterized protein.
 
     0.930
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
     
 0.889
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.882
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.882
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.882
TEP1
Telomerase associated protein 1.
   
 
 0.876
PARP2
Poly [ADP-ribose] polymerase.
     
 0.866
G3U1F5_LOXAF
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.769
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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