SCNN1B protein (Loxodonta africana) - STRING interaction network

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SCNN1B

Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)

Predicted Functional Partners:

SCNN1G

0.997

NEDD4L

0.995

NEDD4

0.991

SCNN1A

0.978

G3TPI0_LOXAF

0.978

SLC26A4

0.728

PRSS8

0.682

SCN2B

0.678

SGK1

0.663

CFTR

0.659

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	G3TPI0_LOXAF	ENSLAFP00000004825	ENSLAFP00000017298	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.417
CFTR	NEDD4	ENSLAFP00000004825	ENSLAFP00000020299	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	E3 ubiquitin-protein ligase.	0.638
CFTR	NEDD4L	ENSLAFP00000004825	ENSLAFP00000009301	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	E3 ubiquitin-protein ligase.	0.552
CFTR	SCNN1A	ENSLAFP00000004825	ENSLAFP00000000612	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.417
CFTR	SCNN1B	ENSLAFP00000004825	ENSLAFP00000001718	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.659
CFTR	SCNN1G	ENSLAFP00000004825	ENSLAFP00000017439	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.569
CFTR	SLC26A4	ENSLAFP00000004825	ENSLAFP00000008809	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.489
G3TPI0_LOXAF	CFTR	ENSLAFP00000017298	ENSLAFP00000004825	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.417
G3TPI0_LOXAF	NEDD4	ENSLAFP00000017298	ENSLAFP00000020299	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase.	0.931
G3TPI0_LOXAF	NEDD4L	ENSLAFP00000017298	ENSLAFP00000009301	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase.	0.970
G3TPI0_LOXAF	SCN2B	ENSLAFP00000017298	ENSLAFP00000002193	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Sodium voltage-gated channel beta subunit 2.	0.727
G3TPI0_LOXAF	SCNN1A	ENSLAFP00000017298	ENSLAFP00000000612	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.561
G3TPI0_LOXAF	SCNN1B	ENSLAFP00000017298	ENSLAFP00000001718	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.978
G3TPI0_LOXAF	SCNN1G	ENSLAFP00000017298	ENSLAFP00000017439	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.980
G3TPI0_LOXAF	SGK1	ENSLAFP00000017298	ENSLAFP00000010620	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Non-specific serine/threonine protein kinase.	0.575
NEDD4	CFTR	ENSLAFP00000020299	ENSLAFP00000004825	E3 ubiquitin-protein ligase.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.638
NEDD4	G3TPI0_LOXAF	ENSLAFP00000020299	ENSLAFP00000017298	E3 ubiquitin-protein ligase.	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.931
NEDD4	NEDD4L	ENSLAFP00000020299	ENSLAFP00000009301	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.947
NEDD4	SCNN1A	ENSLAFP00000020299	ENSLAFP00000000612	E3 ubiquitin-protein ligase.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.931
NEDD4	SCNN1B	ENSLAFP00000020299	ENSLAFP00000001718	E3 ubiquitin-protein ligase.	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.991

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