STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (402 aa)    
Predicted Functional Partners:
TNFSF11
Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.
   
 0.998
G3TBU1_LOXAF
Uncharacterized protein.
   
 0.734
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 0.681
TNFSF14
Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family.
   
 0.635
BTLA
B and T lymphocyte associated.
   
 0.604
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.584
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 0.555
TNFSF15
TNF superfamily member 15.
   
 0.555
FOSL1
FOS like 1, AP-1 transcription factor subunit.
      
 0.551
TNFRSF11A
TNF receptor superfamily member 11a.
   
0.521
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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