STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)    
Predicted Functional Partners:
DDX1
DEAD-box helicase 1.
   
 0.970
RTRAF
RNA transcription, translation and transport factor.
   
 0.934
FAM98B
Family with sequence similarity 98 member B.
    
 0.931
C2orf49
Chromosome 2 open reading frame 49.
    
 0.912
RTCA
RNA 3'-terminal phosphate cyclase.
  
  
 0.875
G3U612_LOXAF
AlbA_2 domain-containing protein.
   
 0.820
TRPT1
tRNA phosphotransferase 1.
     
 0.773
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
  
 0.767
EIF1AX
Eukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
      
 0.723
RCL1
RNA terminal phosphate cyclase like 1.
  
  
 0.722
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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