Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRCProtein tyrosine phosphatase receptor type C. (1291 aa)    
Predicted Functional Partners:
CD22
CD22 molecule.
   
 0.967
SEMA4D
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.964
LCK
Tyrosine-protein kinase.
   
 0.958
HCK
Tyrosine-protein kinase.
   
 0.958
LYN
Tyrosine-protein kinase.
   
 0.939
LCP2
Lymphocyte cytosolic protein 2.
   
 0.913
ITGB2
Integrin beta.
   
 0.900
FYN
Tyrosine-protein kinase.
   
 0.860
PTK6
Tyrosine-protein kinase.
   
 0.860
CD4
CD4 molecule.
   
 0.855
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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