Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LEFTY2Left-right determination factor. (367 aa)    
Predicted Functional Partners:
NODAL
Nodal growth differentiation factor.
  
 
 0.893
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.813
TGFB3
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.802
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.801
INHBE
Inhibin subunit beta E.
      
 0.700
TAGLN
Transgelin; Belongs to the calponin family.
    
 
 0.580
ESF1
ESF1 nucleolar pre-rRNA processing protein homolog.
      
 0.573
TDGF1
Teratocarcinoma-derived growth factor 1.
   
 0.537
G3SXC4_LOXAF
EGF-like domain-containing protein.
    
 0.515
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.506
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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