Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNH1Ribonuclease/angiogenin inhibitor 1. (461 aa)    
Predicted Functional Partners:
RNASE1
Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family.
   
 
 0.931
PYCARD
PYD and CARD domain containing.
   
 0.777
NLRP6
Uncharacterized protein.
 
  
 
 0.736
MAVS
Mitochondrial antiviral signaling protein.
    
 0.689
AK9
Uncharacterized protein.
   
 
 0.682
G3TCK5_LOXAF
Uncharacterized protein.
   
 
 0.682
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 0.665
BRCC3
BRCA1/BRCA2-containing complex subunit 3.
    
 0.635
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 0.631
CARD8
Uncharacterized protein.
   
 0.610
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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