STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (314 aa)    
Predicted Functional Partners:
NDOR1
NADPH dependent diflavin oxidoreductase 1.
   
 0.977
BOLA1
BolA family member 1; Belongs to the BolA/IbaG family.
    
 
 0.963
GLRX3
Glutaredoxin 3.
   
 
 0.963
BOLA2B
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.899
NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
   
 0.812
ZNF428
Zinc finger protein 428.
      
 0.789
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
    
 
 0.785
UBL7
Ubiquitin like 7.
   
 
 0.766
RGS20
RGS domain-containing protein.
    
   0.757
MAS1
MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.743
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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