STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL17FUncharacterized protein. (160 aa)    
Predicted Functional Partners:
IL17RA
Interleukin 17 receptor A.
    
 0.992
IL17RC
Interleukin 17 receptor C.
    
 0.976
IL17A
Interleukin 17A.
   
 0.971
STAT3
Signal transducer and activator of transcription.
    
 0.824
IL10
Interleukin 10.
   
 
 0.746
IL17RD
Interleukin 17 receptor D.
    
 0.726
IL25
Interleukin 25.
      
 0.720
IL6
Interleukin 6.
     
 0.703
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.672
RORC
RAR related orphan receptor C.
   
 
 0.667
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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