SMUG1 protein (Loxodonta africana) - STRING interaction network

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SMUG1

Single-strand-selective monofunctional uracil-DNA glycosylase 1. (279 aa)

Predicted Functional Partners:

ADAT3

0.848

MBD4

0.829

SMG1

0.803

UNG

0.772

TDG

0.755

TYMS

0.736

APEX1

0.727

NEIL1

0.668

LMO2

0.663

UPRT

0.621

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAT3	SMUG1	ENSLAFP00000017791	ENSLAFP00000001827	Adenosine deaminase tRNA specific 3.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.848
ADAT3	TYMS	ENSLAFP00000017791	ENSLAFP00000012486	Adenosine deaminase tRNA specific 3.	Thymidylate synthetase.	0.684
ADAT3	UPRT	ENSLAFP00000017791	ENSLAFP00000003911	Adenosine deaminase tRNA specific 3.	Uracil phosphoribosyltransferase homolog.	0.617
APEX1	MBD4	ENSLAFP00000017753	ENSLAFP00000008883	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.639
APEX1	NEIL1	ENSLAFP00000017753	ENSLAFP00000005252	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nei like DNA glycosylase 1.	0.501
APEX1	SMUG1	ENSLAFP00000017753	ENSLAFP00000001827	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.727
APEX1	TDG	ENSLAFP00000017753	ENSLAFP00000003183	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Thymine DNA glycosylase.	0.729
APEX1	UNG	ENSLAFP00000017753	ENSLAFP00000011304	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.	0.826
LMO2	SMUG1	ENSLAFP00000007445	ENSLAFP00000001827	LIM domain only 2.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.663
MBD4	APEX1	ENSLAFP00000008883	ENSLAFP00000017753	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.639
MBD4	NEIL1	ENSLAFP00000008883	ENSLAFP00000005252	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Nei like DNA glycosylase 1.	0.533
MBD4	SMUG1	ENSLAFP00000008883	ENSLAFP00000001827	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.829
MBD4	TDG	ENSLAFP00000008883	ENSLAFP00000003183	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Thymine DNA glycosylase.	0.706
MBD4	UNG	ENSLAFP00000008883	ENSLAFP00000011304	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.	0.501
NEIL1	APEX1	ENSLAFP00000005252	ENSLAFP00000017753	Nei like DNA glycosylase 1.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.501
NEIL1	MBD4	ENSLAFP00000005252	ENSLAFP00000008883	Nei like DNA glycosylase 1.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.533
NEIL1	SMUG1	ENSLAFP00000005252	ENSLAFP00000001827	Nei like DNA glycosylase 1.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.668
NEIL1	TDG	ENSLAFP00000005252	ENSLAFP00000003183	Nei like DNA glycosylase 1.	Thymine DNA glycosylase.	0.603
NEIL1	UNG	ENSLAFP00000005252	ENSLAFP00000011304	Nei like DNA glycosylase 1.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.	0.564
SMG1	SMUG1	ENSLAFP00000015623	ENSLAFP00000001827	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	Single-strand-selective monofunctional uracil-DNA glycosylase 1.	0.803

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