Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECM2Extracellular matrix protein 2. (671 aa)    
Predicted Functional Partners:
OGN
Osteoglycin.
   
  
 0.534
DPT
Dermatopontin.
   
  
 0.530
SERPINB1
Serpin family B member 1; Belongs to the serpin family.
   
 
 0.525
SLC14A1
Urea transporter; Belongs to the urea transporter family.
      
 0.479
LRRC8B
Leucine rich repeat containing 8 VRAC subunit B.
  
     0.447
LRRC10
Leucine rich repeat containing 10.
  
     0.447
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
  
     0.427
LRRC18
Leucine rich repeat containing 18.
  
     0.424
GLT8D2
Glycosyltransferase 8 domain containing 2.
   
  
 0.421
C17orf78
Chromosome 17 open reading frame 78.
      
 0.419
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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