Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TENT5ATerminal nucleotidyltransferase 5A. (425 aa)    
Predicted Functional Partners:
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
    
 
 0.856
ELOVL4
Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...]
   
  
 0.700
FAM162B
Family with sequence similarity 162 member B.
   
  
 0.692
TENT4A
Terminal nucleotidyltransferase 4A.
      
 0.560
TMEM167A
Protein kish; Involved in the early part of the secretory pathway.
      
 0.549
USP32
Uncharacterized protein; Belongs to the peptidase C19 family.
      
 0.523
MBTPS2
Membrane bound transcription factor peptidase, site 2.
   
  
 0.517
PLK4
Polo like kinase 4.
    
 
 0.494
WDR7
WD repeat domain 7.
      
 0.473
YPEL5
Protein yippee-like; Belongs to the yippee family.
   
  
 0.428
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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