STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)    
Predicted Functional Partners:
AGR2
Anterior gradient 2, protein disulphide isomerase family member.
   
  
 0.594
HOXB2
Homeobox B2.
      
 0.543
MSX2
Msh homeobox 2.
      
 0.525
ILRUN
Inflammation and lipid regulator with UBA-like and NBR1-like domains.
 
    
 0.513
C5orf30
Chromosome 5 open reading frame 30.
    
   0.495
TDP2
Tyrosyl-DNA phosphodiesterase 2.
    
 
 0.486
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
      
 0.479
PRRX2
Paired related homeobox 2.
      
 0.457
PACSIN1
Protein kinase C and casein kinase substrate in neurons 1.
      
 0.449
FOXJ1
Forkhead box J1.
   
 
 0.440
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.