STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL5Kelch like family member 5. (709 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.906
KEAP1
Kelch like ECH associated protein 1.
    
  0.670
KLHL12
Kelch like family member 12.
    
  0.665
RBX1
Ring-box 1.
    
 0.641
SQSTM1
Sequestosome 1.
    
 0.595
TMEM156
Transmembrane protein 156.
   
  
 0.569
RESF1
Retroelement silencing factor 1.
    
   0.564
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.560
PDS5A
PDS5 cohesin associated factor A.
      
 0.546
WDR19
WD repeat domain 19.
     
 0.539
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.