Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCN2Cellular communication network factor 2. (338 aa)    
Predicted Functional Partners:
CCN1
Cellular communication network factor 1.
   
  
 0.833
LATS1
Large tumor suppressor kinase 1.
      
 0.804
COL1A1
Collagen type I alpha 1 chain.
   
  
 0.804
ANKRD1
Ankyrin repeat domain 1.
   
 
 0.801
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.763
IL6
Interleukin 6.
   
  
 0.693
MMP9
Matrix metallopeptidase 9.
    
 
 0.691
SMAD7
Mothers against decapentaplegic homolog.
      
 0.688
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
      
 0.653
IGFBP7
Insulin like growth factor binding protein 7.
   
  
 0.624
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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