STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCN2Cellular communication network factor 2. (338 aa)    
Predicted Functional Partners:
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.677
FN1
Fibronectin 1.
   
 
 0.631
DCN
Decorin; May affect the rate of fibrils formation.
   
  
 0.609
CCN1
Cellular communication network factor 1.
  
  
0.582
EDN1
Endothelin 1.
   
  
 0.581
SMAD7
Mothers against decapentaplegic homolog.
   
  
 0.565
IGFBP7
Insulin like growth factor binding protein 7.
   
  
 0.564
HSPG2
Heparan sulfate proteoglycan 2.
   
 
 0.562
IL6
Interleukin 6.
   
  
 0.553
COL1A1
Collagen type I alpha 1 chain.
   
  
 0.548
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.