Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
COX7A2Cytochrome c oxidase subunit 7A2. (109 aa)    
Predicted Functional Partners:
COX5B
Cytochrome c oxidase subunit 5B.
   
 0.999
COX7C
Cytochrome c oxidase subunit 7C.
   
 0.999
COX6C
Cytochrome c oxidase subunit 6C.
   
 0.998
COX6A1
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 0.997
COX4I1
Cytochrome c oxidase subunit 4I1.
   
 0.997
COX5A
Cytochrome c oxidase subunit 5A.
   
 0.996
COX2
Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
   
 0.995
G3T2S2_LOXAF
Uncharacterized protein.
   
 0.994
COX7B2
Cytochrome c oxidase subunit 7B2.
   
 0.991
COX7B
Cytochrome c oxidase subunit 7B.
   
 0.991
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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