Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SFI1SFI1 centrin binding protein. (1218 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
    
 0.933
CETN2
Centrin 2.
    
 0.926
CETN3
Centrin 3.
    
 0.870
CETN1
Centrin 1.
    
 0.834
EFCAB11
EF-hand calcium binding domain 11.
    
 0.796
RBKS
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
      
 0.794
CRAMP1
Cramped chromatin regulator homolog 1.
      
 0.792
THAP7
THAP domain containing 7.
      
 0.737
FBXW9
F-box and WD repeat domain containing 9.
      
 0.720
ZNF512B
Zinc finger protein 512B.
      
 0.702
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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