STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCTDopachrome tautomerase. (460 aa)    
Predicted Functional Partners:
TYRP1
Tyrosinase related protein 1.
  
 
0.936
MLANA
Uncharacterized protein.
   
  
 0.801
SLC45A2
Solute carrier family 45 member 2.
   
 
 0.718
MITF
Melanocyte inducing transcription factor.
    
 0.716
GPNMB
Glycoprotein nmb.
      
 0.632
RAB38
RAB38, member RAS oncogene family.
      
 0.625
ASIP
Agouti signaling protein.
      
 0.524
TPCN2
Ion_trans domain-containing protein.
      
 0.443
OCA2
OCA2 melanosomal transmembrane protein.
   
  
 0.443
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.419
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.