Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCTDopachrome tautomerase. (460 aa)    
Predicted Functional Partners:
MLANA
Uncharacterized protein.
   
  
 0.940
TYRP1
Tyrosinase related protein 1.
   
 
  0.869
MGRN1
Mahogunin ring finger 1.
      
 0.811
MITF
Melanocyte inducing transcription factor.
    
 0.771
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.746
SLC45A2
Solute carrier family 45 member 2.
   
 
 0.734
GPNMB
Glycoprotein nmb.
   
 0.642
TMEM200A
Transmembrane protein 200A.
      
 0.617
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
 
 0.592
VMO1
Vitelline membrane outer layer 1 homolog.
   
  
 0.585
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.