Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GZMKGranzyme K; Belongs to the peptidase S1 family. (260 aa)    
Predicted Functional Partners:
C2
Complement C2; Belongs to the peptidase S1 family.
   
 0.903
CFB
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.903
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
     
 0.878
G3T2J6_LOXAF
Uncharacterized protein.
   
 0.846
C3
Complement C3.
   
 0.846
C4A
Uncharacterized protein.
   
 0.846
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
   
  
 0.723
NKG7
Natural killer cell granule protein 7.
   
  
 0.710
CD8A
CD8a molecule.
   
 
 0.627
RETN
Resistin.
   
 
 0.607
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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