STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GZMAGranzyme A; Belongs to the peptidase S1 family. (259 aa)    
Predicted Functional Partners:
PRF1
Perforin 1.
   
 0.759
F2RL2
Coagulation factor II thrombin receptor like 2.
    
  0.719
F2RL1
F2R like trypsin receptor 1.
   
 0.699
PJVK
Pejvakin.
     
 0.672
CD8A
CD8a molecule.
   
 
 0.663
GSDME
Gasdermin E.
     
 0.654
PARD3
Par-3 family cell polarity regulator.
     
  0.650
GSDMD
Gasdermin D.
     
 0.635
CD2
CD2 molecule.
   
 
 0.624
NKG7
Natural killer cell granule protein 7.
   
  
 0.608
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.