BIN2 protein (Loxodonta africana) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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[Homology]

Score

BIN2

Bridging integrator 2. (479 aa)

Predicted Functional Partners:

BIN1

0.948

BIN3

0.873

AMPH

0.831

PACRG

0.797

WAS

0.744

DNM2

0.693

DNM3

0.693

DNM1

0.693

AP2A1

0.637

RIN3

0.618

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPH	AP2A1	ENSLAFP00000013123	ENSLAFP00000025328	Amphiphysin.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.851
AMPH	BIN1	ENSLAFP00000013123	ENSLAFP00000022960	Amphiphysin.	Bridging integrator 1.	0.994
AMPH	BIN2	ENSLAFP00000013123	ENSLAFP00000001999	Amphiphysin.	Bridging integrator 2.	0.831
AMPH	DNM1	ENSLAFP00000013123	ENSLAFP00000017903	Amphiphysin.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.965
AMPH	DNM2	ENSLAFP00000013123	ENSLAFP00000002843	Amphiphysin.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.965
AMPH	DNM3	ENSLAFP00000013123	ENSLAFP00000011126	Amphiphysin.	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.772
AMPH	PACRG	ENSLAFP00000013123	ENSLAFP00000002287	Amphiphysin.	Parkin coregulated.	0.400
AMPH	RIN3	ENSLAFP00000013123	ENSLAFP00000017044	Amphiphysin.	Ras and Rab interactor 3.	0.790
AMPH	WAS	ENSLAFP00000013123	ENSLAFP00000022280	Amphiphysin.	WASP actin nucleation promoting factor.	0.629
AP2A1	AMPH	ENSLAFP00000025328	ENSLAFP00000013123	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Amphiphysin.	0.851
AP2A1	BIN1	ENSLAFP00000025328	ENSLAFP00000022960	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Bridging integrator 1.	0.745
AP2A1	BIN2	ENSLAFP00000025328	ENSLAFP00000001999	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Bridging integrator 2.	0.637
AP2A1	BIN3	ENSLAFP00000025328	ENSLAFP00000015479	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Bridging integrator 3.	0.446
AP2A1	DNM1	ENSLAFP00000025328	ENSLAFP00000017903	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.689
AP2A1	DNM2	ENSLAFP00000025328	ENSLAFP00000002843	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.689
AP2A1	DNM3	ENSLAFP00000025328	ENSLAFP00000011126	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.734
BIN1	AMPH	ENSLAFP00000022960	ENSLAFP00000013123	Bridging integrator 1.	Amphiphysin.	0.994
BIN1	AP2A1	ENSLAFP00000022960	ENSLAFP00000025328	Bridging integrator 1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.745
BIN1	BIN2	ENSLAFP00000022960	ENSLAFP00000001999	Bridging integrator 1.	Bridging integrator 2.	0.948
BIN1	BIN3	ENSLAFP00000022960	ENSLAFP00000015479	Bridging integrator 1.	Bridging integrator 3.	0.873

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