STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (591 aa)    
Predicted Functional Partners:
SIX5
SIX homeobox 5.
   
 
 0.803
SIX1
SIX homeobox 1.
   
 
 0.782
DACH1
Dachshund family transcription factor 1.
    
 
 0.711
SIX4
SIX homeobox 4.
   
 
 0.620
G3UMV3_LOXAF
Homeobox domain-containing protein.
   
 
 0.576
SALL1
Spalt like transcription factor 1.
      
 0.574
CHD7
Chromodomain helicase DNA binding protein 7.
      
 0.501
PAX7
Paired box 7.
    
 
 0.447
CNMD
Chondromodulin.
      
 0.446
SIX6
SIX homeobox 6.
   
 
 0.444
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.