STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L2Signal induced proliferation associated 1 like 2. (1721 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.867
G3T8N8_LOXAF
Uncharacterized protein.
    
 0.810
RAP1B
Uncharacterized protein.
    
 0.810
WDR27
Uncharacterized protein.
    
 0.775
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.740
SIPA1
Signal-induced proliferation-associated 1.
    
 
 0.736
LZTS1
Leucine zipper tumor suppressor 1.
    
 
 0.722
SIPA1L1
Signal induced proliferation associated 1 like 1.
    
 
 0.708
SIPA1L3
Signal induced proliferation associated 1 like 3.
    
 
 0.684
AFDN
Afadin, adherens junction formation factor.
   
 0.658
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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