STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNE1Uncharacterized protein. (129 aa)    
Predicted Functional Partners:
KCNQ1
Ion_trans domain-containing protein; Belongs to the potassium channel family.
    
 0.990
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
     
 0.929
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
     
 0.929
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
    
 0.683
KCNE4
Uncharacterized protein.
      
 0.682
NOS1AP
Nitric oxide synthase 1 adaptor protein.
      
 0.609
KCNE3
Potassium voltage-gated channel subfamily E regulatory subunit 3.
      
 0.577
KCNQ3
Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.
    
 0.511
KCNQ2
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
    
 0.490
NEDD4
E3 ubiquitin-protein ligase.
      
 0.487
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.