Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRLS1Cardiolipin synthase 1. (266 aa)    
Predicted Functional Partners:
TAZ
Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism.
     
 0.940
PGS1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
  
 
 0.935
LCLAT1
Lysocardiolipin acyltransferase 1.
  
 
 0.925
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 0.918
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.917
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
  
 
 0.914
LPGAT1
Lysophosphatidylglycerol acyltransferase 1.
  
 
 0.910
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
  
 
 0.890
LOC100659656
Uncharacterized protein.
  
 
 0.887
PDS5A
PDS5 cohesin associated factor A.
      
 0.884
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.