Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBLIFCobalamin binding intrinsic factor. (418 aa)    
Predicted Functional Partners:
CUBN
Cubilin.
    
 0.991
ATP4B
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
  
 0.811
CDCP2
CUB domain containing protein 2.
    
 0.795
GALNT5
Polypeptide N-acetylgalactosaminyltransferase.
    
   0.720
AMN
Amnion associated transmembrane protein.
     
 0.697
G3TMX8_LOXAF
Uncharacterized protein.
    
 0.630
VEGFB
Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.
   
  
 0.597
GAST
Gastrin.
      
 0.563
TFF2
Trefoil factor 2.
   
  
 0.558
G3UH06_LOXAF
Uncharacterized protein.
      
 0.546
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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