STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL2Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (303 aa)    
Predicted Functional Partners:
G3SP06_LOXAF
Uncharacterized protein.
      
 0.682
EFNB3
Ephrin B3; Belongs to the ephrin family.
    
 
 0.602
ANKRD22
Ankyrin repeat domain 22.
      
 0.601
EPHB4
EPH receptor B4.
   
 
 0.586
G3T5G6_LOXAF
Rhomboid domain-containing protein.
      
 0.574
EFNB2
Ephrin B2; Belongs to the ephrin family.
    
 
 0.492
PSENEN
Uncharacterized protein.
      
 0.491
NCSTN
Nicastrin.
      
 0.489
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
   
 
 0.462
RHBDD1
Rhomboid domain containing 1.
      
 0.459
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.