Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPON1Spondin 1. (727 aa)    
Predicted Functional Partners:
B3GLCT
Beta 3-glucosyltransferase.
     
 0.743
POFUT2
Protein O-fucosyltransferase 2.
     
 0.718
VSTM2L
V-set and transmembrane domain containing 2 like.
      
 0.624
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.505
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.505
APP
Amyloid beta precursor protein.
   
 
 0.504
CSTF3
Cleavage stimulation factor subunit 3.
      
 0.504
ZNF385B
Zinc finger protein 385B.
      
 0.500
ANLN
Anillin actin binding protein.
      
 0.496
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
      
 0.484
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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