Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANXA4Annexin. (319 aa)    
Predicted Functional Partners:
S100A10
S100 calcium binding protein A10; Belongs to the S-100 family.
   
 0.586
G3U568_LOXAF
EF-hand domain-containing protein; Belongs to the S-100 family.
   
 0.586
ANXA2
Annexin.
   
  0.580
CD9
Tetraspanin.
   
 
 0.569
ANXA1
Annexin.
   
  0.518
TUBA4A
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
   
 0.504
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
      
 0.493
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 
 0.479
TUBB
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.
    
 
 0.470
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 
 0.468
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.