STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDP2Tyrosyl-DNA phosphodiesterase 2. (352 aa)    
Predicted Functional Partners:
TDP1
Tyrosyl-DNA phosphodiesterase 1.
   
  
 0.786
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
   0.761
POLA2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
      
 0.682
RPS27A
Ubiquitin-like domain-containing protein.
    
   0.663
G3U9C8_LOXAF
Ubiquitin-like domain-containing protein.
    
   0.663
LIG1
DNA ligase.
      
 0.654
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
      
 0.639
NIT1
Nitrilase 1.
      
 0.636
ZNF451
Zinc finger protein 451.
      
 0.634
UNG
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
   
  
 0.625
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.