Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THBS1Thrombospondin 1. (1169 aa)    
Predicted Functional Partners:
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.957
CD47
CD47 molecule.
   
 0.956
CD36
CD36 molecule; Belongs to the CD36 family.
    
 0.949
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.932
MMP9
Matrix metallopeptidase 9.
    
 0.927
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.913
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.912
LTBP1
Latent transforming growth factor beta binding protein 1.
   
 
 0.911
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.911
ID1
Inhibitor of DNA binding 1, HLH protein.
    
 0.908
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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